Viagra wiki:

Ingredients, How to Use and Alternatives


Viagra Wiki

Everyone wants to have a good time in bed. But sometimes, people’s physical capabilities reach their limits and their sex life might not be so much interesting without some extrinsic stimulation. This is why men have been trying to come up with recipes that can positively influence sex. These come in all kind of forms. Some alter their diets and others even go as far as experimenting with herbs. Some of these nonconventional medications have worked, but others have been a disappointment because they come with atrocious side effects. Nevertheless, it is a good thing that there is a lot of input to try and make life better. Today, we can speak of success because, towards the end of the twentieth century, the wonder drug named Viagra was discovered.

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What is Viagra?

The discovery of Viagra was greeted with excitement because for once a drug had been approved for treating erectile dysfunction. However, the name Viagra has been used widely to describe any ED med, leaving a vague answer to the question ‘whats Viagra?’ Scientists at Pfizer Laboratories were trying to come up with a drug for angina pectoris, but they ended up inventing something else. Angina pectoris is the clinical term for chest pains that come as a result of an ischemic heart disease. However, things turned out differently when clinical trials were done on the drug. A few minutes after oral administration, Viagra caused hard erections on a significant percentage of the subjects. The turn of events was unexpected, and the drug that Pfizer developed had a relatively milder effect on angina pectoris than on erection disorders. After a series of discussions, Pfizer decided that they would market Viagra as an erectile dysfunction drug rather that a remedy for angina pectoris. And that’s how Viagra became the ED drug that has been famed all over.

As you would expect, Pfizer did not dump its angina pectoris studies into a bin. Besides Viagra, Pfizer came up with a medication named Revatio which is used to treat pulmonary hypertension. Revatio has also been proven to increase the exercise capability of its users.

In the 90s, Pfizer decided to claim exclusive patent on Viagra and Revatio so that they could enjoy the fruits of their labor before other manufacturers popped in. The inventor of Viagra got the patent and for about a decade, Pfizer enjoyed exceptional dominance of the market, and it made remarkable sales. In 2012, Pfizer made a whopping $2000 million revenue from the sale of Viagra.

However, in 2013, the exclusive patent on Viagra expired in many countries, and the market changed considerably. Makers of generic Viagra popped up in many parts of the world, especially Europe and Asia. These generic meds are sold at very low prices, and they are getting buyers as well. This means that the brand name Viagra is losing some of its buyers, and it’s only a matter of time before the loyal ones also decide to start spending less on eradicating their erectile dysfunction concerns. Currently, the market is flooded with Viagra-like products which have also been proven to produce excellent results. For countries like the US where the patents are still active, the market is a little tight, but the buyers can still import the cheap ED pills from neighboring nations like Canada.

Viagra Ingredients (sildenafil citrate)

Sildenafil citrate is what Pfizer discovered and named Viagra. This substance is responsible for the effect Viagra produces on the body, and it is thus the active ingredient in Viagra. Many other drugs that mimic the effects of Viagra are also sildenafil citrate-based. Sildenafil citrate interacts with receptors on the penile blood vessel walls. The interaction results in inhibition of the enzyme phosphodiesterase 5 (PDE 5) which is responsible for the breakdown of cGMP. cGMP is an acronym for Cyclic guanosine monophosphate. This compound is responsible for keeping the blood vessel walls dilated, so when it is degraded by PDE 5, the vessels collapse. The sildenafil citrate, therefore, ensures that the vessel walls remain dilated for as long as it is stays active in the body. The effect that will be seen and felt from the outside is a hard erection because a lot of blood can now flow to the penis. The erection also lasts longer because cGMP remains in its active state for a longer period. Because of the presence of sildenafil citrate in most ED drugs, the generic Viagra meds are commonly referred to as sildenafil pills.

There is more to Viagra ingredients than the active ingredient sildenafil citrate. Other inactive ingredients accompany sildenafil citrate just to make it more efficient and improve some of its pharmacokinetic properties. However, these inactive ingredients do not have a significant influence on the erectile dysfunction symptoms, and they also have little bearing on side effects unless one has allergies to any one of them. The excipients in Viagra are microcrystalline cellulose, lactose, anhydrous dibasic calcium phosphate, magnesium stearate, hypromellose, croscarmellose sodium, titanium dioxide and triacetin.

The color of sildenafil citrate is crystalline white but what does Viagra look like (brand Viagra)? It comes as blue diamond-shaped pills. The reason is that there are also coloring ingredients in the drug. C Blue Aluminum Lake is the ingredient that brings out the blue color in Viagra.

How to Use Viagra

For maximum benefits, Viagra should be utilized appropriately. It is good practice to use the drug only as a prescription medicine rather than buying over the counter and popping it at one’s own discretion. However, some of the generic pills have few restrictions on them, and they can be obtained without a prescription. The dosage is best determined by qualified personnel. In most cases, the starting dosage is 50mg per intake which is administered once a day. Later, the dosage can be adjusted depending on the response that was observed with the use of the 50mg tablet. If there was some tolerance elicited and weakening of function observed, then the dosage should be raised to 100mg. In the opposite case, the dose is lowered to 25mg.

Viagra takes some time after ingestion before the onset of its action. On average, the effect will be felt 30 minutes after oral administration. Therefore, it's nice to take the pills about an hour before expected sexual activity. The ED pills can be taken with or without food. However, it is worth noting that when a fatty diet accompanies the ingestion of Viagra, the onset of action is delayed. After the onset of action, the effects of the drug are felt for about four hours and then they fade off.

A hard erection does not simply come with the ingestion of Viagra. There has to be sexual stimulation for the effects to be felt. It is a good point of convenience because things don’t always go as planned. You can take the pills and then an emergency comes by. Since there will be no sexual stimulation at this moment, you can attend to your issues with the sildenafil citrate still running in your veins.

Viagra pills should be swallowed in their solid form. They should not be chewed or crushed. The pills should also be taken with a lot of water to facilitate maximum absorption into the system.

Is Viagra Safe?

The question regarding the safety of Viagra has been raised on very many occasions. Is Viagra safe? If used as recommended, the impotence drug does not have adverse outcomes. Like any other drug, Viagra has its contraindications. This is the reason why a health expert should be involved in the prescription of the drug because they can determine whether or not to deem Viagra safe in a particular condition.

In patients with known allergies to sildenafil citrate and other ingredients contained in Viagra, the drug should not be prescribed because it will lead to undesirable reactions. Some of the reported hypersensitivity reactions resulting from Viagra use are urticaria and rashes. People with cardiovascular conditions such as coronary ischemia, low blood pressure, and congestive cardiac failure should not use Viagra. Several deaths have been reported due to the use of sildenafil citrate among cardiac patients. Therefore, it is safe to avoid using the drug altogether. Those with liver failure should also avoid using Viagra because Sildenafil citrate is metabolized by liver enzymes. Individuals with bleeding disorders should also avoid using Viagra because platelets too have PDE 5 which is inhibited by sildenafil citrate. People with renal impairment have poor clearance of sildenafil meaning that it could accumulate and, potentially, reach unwanted levels in their systems.

The safety of Viagra is further affected by interaction with other chemicals and substances in the body. Earlier, it was pointed out that when taken with a fatty diet, Viagra will take longer to start acting. Among the most common drug interactions is that with nitrates. Nitrates and other NO donors act to dilate blood vessels. They are therefore used as antihypertensives. The concomitant use of Viagra with nitrate compounds, therefore, makes the hypotensive effects even stronger. Other PDE inhibitors also interact with sildenafil citrate. Of note are the PDE 3 inhibitors which when used together with Viagra, could cause hypotension, cardiotoxic and haemorrhagic complications. Sildenafil is metabolized by cytochrome P450. When other drugs that inhibit this pathway are taken with Viagra, the plasma concentration of sildenafil rises.

In cases of overdose, the adverse reactions that are associated with Viagra tend to occur more frequently, and they are more severe. Only one pill should be taken within 24 hours. Sildenafil is highly protein bound. Therefore, renal dialysis will not help to clear the drug from the system in cases of overdose. However, medical attention should be sought so that the necessary supportive therapy is initiated.

To avoid complications, always buy genuine Viagra pills. If you are buying the generic meds, ensure you get them from a trusted vendor. Counterfeit medications are dangerous to use because they are not tested and approved. Such drugs could have awful side effects if taken.

Where to Buy Viagra

Viagra can be purchased similarly to any other medication. The old way is buying from a brick-and-motor pharmacy down the street. This is how the drug was purchased in the early times, just after its discovery. But there is always that embarrassment that comes along when you are buying from a pharmacy. It is even worse when the pharmacist asks for a prescription and it turns out you don’t have one.

Online pharmacies are also in the picture thanks to today’s population which spends a significant portion of its time surfing the internet. There are a large number of e-pharmacies that sell Viagra online, and you can place your order anytime from anywhere. With these, you just have to be sure that you will get your delivery on time. The online vendor should be reputable and within your reach unless what you want to buy is not found in your locality. There have been reported cases of people who order Viagra pills, and they never get their delivery. Others who order from abroad have their products held at the customs due to some bureaucratic issues. Still, online purchase is very convenient because you don’t have to walk to a pharmacy and struggle to explain yourself. Some of the online pharmacies do not require a prescription, and even those that require will not be so hard on you. They can generate one for you after you answer some of their questions.

Viagra.com is one of the vendors of Viagra that has been on the market for a long time and their products have been proven to be genuine. This is the official website run by Pfizer Inc. The site has fantastic discounts on Viagra, and any eligible person can place an order as long as they have a prescription. Viagra.com also helps its users find the right dosage. Besides selling, this website also has some other educative info on Viagra which consumers can use to better their utilization and find optimum results.

You can also buy Viagra from classified advertisement websites such as Craigslist. However, the experts do not advocate for this. Some ads are also sent to you via email, and if you are too busy to search around the internet, then you can go for this although it is not encouraged.

Viagra Alternatives

Viagra is not the only ED drug on the market. If you want a different taste, you can check out some of the Viagra alternatives. Here are some of the other options that are available.

Cialis

Cialis, manufactured by Eli Lilly, is a tadalafil-based oral drug that is used for the treatment of erectile dysfunction and benign pulmonary hyperplasia. Cialis comes in different strengths such as 2.5mg, 5mg, 10mg, and 20mg. It is taken once a day and the strength of choice depends on the condition of ED. Some people are prescribed a 10mg initial dose and later a maintenance dose of between 5mg and 20mg. In other cases, when Cialis is used as a daily pill, the initial dose is 2.5mg and the maintenance dose is between 2.5 to 5mg. The use of Cialis with alcohol is contraindicated.

Levitra

Levitra is a drug made of Vardenafil which is a PDE 5 inhibitor just like sildenafil. It is co-marketed by three parties; GlaxoSmithKline, Bayer Pharmaceuticals, and Schering-Plough. The drug relaxes blood vessel walls and allows more blood flow. Therefore, it is used to treat erectile dysfunction because it can increase the amount of blood being channelled to the penis. Levitra is FDA-approved, and it is used as a prescription-only med. The tablets come in strengths of 2.5mg, 5mg, 10mg, and 20mg.

Generic Viagra

Generic Viagra refers to other sildenafil-based meds other than the brand name Viagra. These drugs came into existence after the expiry of the exclusive patent that Pfizer Inc. had on sildenafil as an ED medication. In some countries, the patent was never enforced, and generic Viagra has been circulating for a long time.

Generic Viagra, as long as they are approved by relevant food and drug authorities, are as effective as the brand name pills. The advantage of buying generic sildenafil is their low price. Many manufacturers have come into the picture, but there are also some counterfeits which are riding on the backs of the legit generic Viagra. Consumers of generic sildenafil should be very careful when purchasing the drugs.

Viagra is a wonderful development in the health sector, and we can’t thank Pfizer enough. No one intentionally imposes erectile dysfunction upon themselves. Sometimes it is because of age or prostate resection, therefore, a remedy for such situations is surely something to be grateful for. However, the proper use of Viagra should be observed. If abused, the blue diamond pills can produce unpleasant or downright damaging effects. For those who have opted to use the generic variants, caution should be taken as you buy. Just ensure you are buying nothing short of sildenafil. With this in mind, ED will soon become a problem of the past for you.

Is It Safe To Buy Viagra from India?

Generics: Protect Your Wallet

Erectile dysfunction is by far the most common disease in the male sexual sphere among adult males around the whole world. Naturally, people with different income levels face this trouble, many of whom are not ready to pay impressive amounts for branded drugs to improve potency, because the cost of one pill of Viagra, which is the most popular drug used to treat erectile dysfunction, can reach twelve dollars. Due to the fact that each sexual act is costing such a sum, many men refuse treatment, which leads to aggravation of their condition and a significant deterioration in the quality of life.

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Buy cheap Viagra online from Canadian pharmacy

Everyone knows that drugs are expensive. And drugs for erectile dysfunction are traditionally one of the most expensive, especially if a man is forced to use them regularly. Manufacturers are betting on the fact that in an effort to restore their potency, men will not spare money for expensive branded drugs. The recognized leader in efficiency as well as in the ability to empty wallets is Viagra, produced by the American pharmaceutical corporation Pfizer.

However, many patients suffering from potency disorders simply don’t have the necessary money to buy Viagra. In addition, when drugs are so expensive, there is a real danger that sex will cease to look in the eye of the patient as attractive as before. But quality sex is the main component of a happy life for any man, no matter what they say about the importance of work, love and hobbies.

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Bacterial vaginosis, also called BV or nonspecific vaginitis, is a common infection of the female lower genital tract. In women of reproductive age, BV is the commonest cause of vaginal discharge. Other vaginal diseases that cause a discharge include candidiasis, trichomoniasis, and cervicitis.

Bacterial vaginosis is usually observed when there is an imbalance of the bacterial populations that are normally found in the vagina. The imbalance can be triggered by douching, taking antibiotics, and the use of an intrauterine device.

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How to Treat BV Over the Counter

What is Bacterial Vaginosis? Bacterial Vaginosis, also referred to as vaginitis or non-specific vaginitis, is a mild infection that is brought about by an imbalance of certain types of bacteria in the vagina. Typically, the vagina has ‘good’ (healthy) and ‘bad’ bacteria; the former being the ones that keep the latter in check. Should the balance of good bacteria and bad bacteria be upset, for one reason or another, leaving the bad bacteria to thrive, BV develops. It is normally characterized by a vaginal discharge with foul odor.

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